Yeah, i have to strongly disagree with Russian Wolf on this one.

I've been testing hundreds of pheromone formulas(or singles) on the same people for years and years, and my test subjects, most of the time, react according to the new and different signature(s).

But I also know where you coming from, nothing beats a clean slate test subject when it comes to reactions.

I have gotten bad results from wearing AV solo around the friends I know for a long time and they gave me a different vibe like they didn't recognize me. They kinda stayed away from me and didn't engage with me.

AV is best used with new people which gave me consistent results.

As for other mones, Wolf, NA, or BW around longtime friends would be useful. AV is just one exception out of all LAL mones.