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Relationship between stress and efficacy
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extraballislit
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Post: #31
RE: Relationship between stress and efficacy
05-13-2012 1:30 AM

What good be a good nootropic combo for a first time user?

I was thinking piracetam and choline, but some of you seem to be pretty experienced. Any guidance about dosages and cycles would be great.

Alos, I'm curious... Do you think nootropics can somehow alter the self effects of mones?

Thanks.

Talk to you soon.
05-13-2012 1:30 AM
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zerosix85
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Post: #32
RE: Relationship between stress and efficacy
05-13-2012 2:16 AM

Ripped from another source but this gives you an idea.

Piracetam (2-oxo-Pyrrolidine Acetamide) - is a derivative of the neurotransmitter GABA (Gamma Amino Butyric Acid). Chemically related to the amino acid Pyroglutamic Acid (Pyrrolidine Carboxylic acid), which occurs in cerebrospinal fluid and plays an important role in cognitive functioning.

Aniracetam - Aniracetam (1-Anisoyl-2-pyrrolidinone) is a fat soluble potent analog of Piracetam. Because it is fat soluble, it's stronger with the same dosage, though has a much shorter period of working. Based on vague research, seems to be the 'ram with the least anxiety-inducing effects at high doses.

Oxiracetam - (4-hydroxy-2-oxo-1-pyrrolidinacetamide) is a water soluble analog of Piracetam

Pramiracetam
- (N-{2-(diisopropylamino)ethyl}-2-oxo-1-pyrrolidine-acetamide) is at least 10 times stronger than the same amount of Piracetam

Piracetam and Oxiracetam are both water soluble meaning that you can drink water with it to absorb it through your body. The con, it takes minimum of 2 weeks to build up in your body to start feeling the effects.

Aniracetam and Pramiracetam are both fat soluble. So you would need fish oil, peanut butter or any kind of foods that are high in fat to increase absorption. These racetams are faster acting and you will notice their effects immediately.

Also if you take racetams, I know people always suggest to take it with a choline source which is fine but if you do, don't over do it. Overextended and overuse of choline can have depressive effects also .

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05-13-2012 2:16 AM
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Post: #33
RE: Relationship between stress and efficacy
05-13-2012 10:47 AM

For what it's worth, piracetam has a VERY different shape than GABA.

piracetam
http://en.wikipedia.org/wiki/File:Piracetam.svg

GABA
http://en.wikipedia.org/wiki/File:Gamma-...c_acid.svg

Thanks for the solubility info, though. I'd been trying aniracetam with water. I'll have to change that.

If I've never gotten a depressive effect from choline, what might that indicate?

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(This post was last modified: 05-13-2012 10:49 AM by wiserd.)
05-13-2012 10:47 AM
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Post: #34
RE: Relationship between stress and efficacy
05-13-2012 11:58 AM

Like anything else, too little or too much is bad for you. If you don't get depressed from taking choline then it probably means that your choline intake is sufficient or I can't speak for you. If you wanted to take a Choline supplement then try:

Lechitin
DMAE Bitartrate
Choline Bitartrate
CDP-Choline
Alpha-GPC

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05-13-2012 11:58 AM
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Post: #35
RE: Relationship between stress and efficacy
05-15-2012 5:09 PM

(05-07-2012 11:16 AM)dbot Wrote:  Sorry, I'll stop hijacking this thread now Big Grin

That's cool, I'm just stoked it got you guys talking about something you obviously enjoy! Smile Go for it man, do it up!

~Op
(This post was last modified: 05-15-2012 5:10 PM by OpR8R.)
05-15-2012 5:09 PM
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