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Hormones and sensitivity to androsterone
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jvkohl
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Post: #1
Hormones and sensitivity to androsterone
01-16-2013 6:51 PM

This reverse chronology takes the new finding of increased olfactory sensitivity to androsterone and links it to the epigenetic effects of androstenol on luteinizing hormone (LH), on mood, on women's observed flirtatious behaviors and on their self-reported increased attraction to a man wearing the androsterone/androstenol mix, which is found in the "Scent of Eros" roll-on product for men, and in "The Mind's Eyes" spray.

The chronology does not prove that these products enhance the appeal of the man wearing them, but that claim now has more scientific support behind it than there has ever been for any human pheromone-enhanced product. If you want to see the scientific support, look at the links below. If, as a consumer, you are willing to buy whatever product is accompanied by the best marketing claim, you are part of the problem I've had sticking to the science.

2013 The Relationship Between Oral Contraceptive Use and Sensitivity to Olfactory Stimuli
Excerpt 1: "Previous work has found that women rate a man's scent as a particularly important factor in selecting a potential mate"”of greater importance than a man's physical appearance and voice, as well as many other factors, such as how many friends he has or how much money he earns (Herz & Inzlicht, 2002)." Excerpt 2: "In the present study, hormonal status was found only to affect olfactory sensitivity to the social odors, musk, androsterone and androstenone."

2012 Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors Excerpt: "The concept that is extended is the epigenetic tweaking of immense gene networks in "˜superorganisms' (Lockett, Kucharski, & Maleszka, 2012) that "˜solve problems through the exchange and the selective cancellation and modification of signals (Bear, 2004, p. 330)'. It is now clearer how an environmental drive probably evolved from that of food ingestion in unicellular organisms to that of socialization in insects. It is also clear that, in mammals, food odors and pheromones cause changes in hormones such as LH, which has developmental affects on sexual behavior in nutrient-dependent, reproductively fit individuals across species of vertebrates."

Unpublished Human pheromones, epigenetics, physiology, and the development of animal behavior
Excerpt: Our [androstenol/androsterone] mixture characterizes species-specific human pheromones, their epigenetic effects on physiology, and their affect on behavior. Our results are consistent with a validated, unaltered, decades-old, across-species concept of pheromones.

2003 Male axillary extracts contain pheromones that affect pulsatile secretion of luteinizing hormone and mood in women recipients Abstract excerpt: Pulses of LH are excellent indicators of the release of GnRH from the brain's hypothalamus. In women, the positive influence of GnRH on LH affects the length and timing of the menstrual cycle, which, in turn, affects fertility. Here we show that extracts of male axillary secretions have a direct effect upon LH-pulsing and mood of women.

2001 Axillary pheromones modulate pulsatile LH secretion in humans Abstract excerpt: "...in humans, pheromones may play a role in the modulation of the timing of ovulation by changing the frequency of pulsatile LH secretion."

2000 Effects of 5alpha-androst-16-en-3alpha-ol on the pulsatile secretion of luteinizing hormone in human females Excerpt 1: "the present results suggest that [5alpha-androst-16-en-3alpha-ol] 3alpha-androstenol may be a pheromone included in the axillary compounds..." Excerpt 2: "The frequency of the LH pulse in the follicular phase was decreased by exposing the women to 3alpha-androstenol."

1996 From fertilization to adult sexual behavior Abstract excerpt: 'All these factors affect the internal workings of the individual and intervene in structuring how the social environment might or might not modify sexual behavior.' "...the mammalian model, including human studies, supports a role for chemosensory communication that appears to extend to a causal relationship among human pheromones, olfaction, the hypothalamic GnRH pulse, other hormones, including steroid hormones, and human behavior (Kohl, 1996).

James V. Kohl
Clinical Laboratory Scientist (ASCLS)
Medical Laboratory Scientist (ASCP)
Medical Technologist (AMT)
Author/Creator: The Scent of Eros
01-16-2013 6:51 PM
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