Hello There, Guest! Register

Or login with facebook connect Facebook, or Windows Live

Login or Register to remove all advertising



1 user browsing this thread: (0 members, and 1 guest).

Post Reply 
 
Thread Rating:
  • 0 Votes - 0 Average
  • 1
  • 2
  • 3
  • 4
  • 5
Androstenol - a Steroid Derived Odor Activates the Hypothalamus in Women
Author Message
zeph
Offline
=]




Joined: Aug 2009
Sex: Male
Posts: 239

Reputation: 4316
Rep Post

Thanks Given: 87
Thanks received:
81 thanks in 49 posts



Post: #1
Androstenol - a Steroid Derived Odor Activates the Hypothalamus in Women
05-23-2010 2:26 PM

mmm, I have access to UCI's Library and all their subscriptions to various journals across all fields of research (via a friend, alumni have to pay to have access :[ )

Here's an abstract of the article.

Androstenol - a Steroid Derived Odor Activates the Hypothalamus in Women

Author(s): Savic, Ivanka (ivanka.savic-berglund@ki.se); Berglund, Hans
Source: PLoS One Volume: 5 Issue: 2 Pages: Article No.: e8651 Published: FEB 17 2010
Abstract: Background: Whether pheromone signaling exists in humans is still a matter of intense discussion. In the present study we tested if smelling of Androstenol, a steroid produced by the human body and reported to affect human behavior, may elicit cerebral activation. A further issue was to evaluate whether the pattern of activation resembles the pattern of common odors.Methodology: PET measurements of regional cerebral blood flow (rCBF) were conducted in 16 healthy heterosexual women during passive smelling of Androstenol, four ordinary odors (OO), and odorless air (the base line condition).Principal findings: Smelling Androstenol caused activation of a portion of the hypothalamus, which according to animal data mediates the pheromone triggered mating behavior. Smelling of OO, on the other hand, engaged only the classical olfactory regions (the piriform cortex, lateral amygdala, anterior insular and anterior cingulate cortex).Conclusions: The observed pattern of activation is very similar to the pattern previously detected with 4,16-androstadien-3-one in heterosexual females. It suggests that several compounds released by human body may activate cerebral networks involved in human reproduction.
Accession Number: PREV201000173431
Document Type: Article
Language: English
Address: Savic, Ivanka ; Karolinska Inst, Stockholm Brain Inst, Dept Clin Neurosci, Stockholm, Sweden
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0008651
05-23-2010 2:26 PM
Find all posts by this user Quote this message in a reply
Login or register to remove all advertising

jvkohl
Offline
Expert




Joined: Aug 2009
Sex: Male
Posts: 422

Reputation: 10330
Rep Post

Thanks Given: 30
Thanks received:
303 thanks in 134 posts



Post: #2
RE: Androstenol - a Steroid Derived Odor Activates the Hypothalamus in Women
05-30-2010 9:02 PM

The full text of the article is available for free from the following URL

http://www.plosone.org/article/info:doi/...ne.0008651

Also available for free is:
Effects of 5alpha-androst-16-en-3alpha-ol on the pulsatile secretion of luteinizing hormone in human females. Shinohara K, Morofushi M, Funabashi T, Mitsushima D, Kimura F. Chem Senses. 2000 Aug;25(4):465-7.
http://chemse.oxfordjournals.org/cgi/reprint/25/4/465

A few years ago, some colleagues showed that male axillary secretions alter (LH) luteinizing hormone levels (and mood) in women. Free at: http://www.biolreprod.org/content/68/6/2107.long

All this is not surprising to those who have followed my work. My first presentation (in 1992) was Luteinizing hormone (LH): the link between sex and the sense of smell. In 2007 I detailed the evolution of the neurophysiological mechanism that links LH to sex and the sense of smell. Free at:
http://www2.hu-berlin.de/sexology/BIB/kohl.htm

Meanwhile, most of the marketers are still telling consumers about how human pheromones act via a nonfunctional human VNO. I perceive the need for some education of the masses, who might someday start reading the available literature. Thanks for citing one of the most pertinent recent articles. There are a few more coming from different research groups that have already presented their findings at different conferences, but have not yet published.

James V. Kohl
http://www.pheromones.com
(This post was last modified: 05-30-2010 9:26 PM by jvkohl.)
05-30-2010 9:02 PM
Visit this user's website Find all posts by this user Quote this message in a reply

Share This Thread
Del.icio.us Digg FURL FaceBook Stumble Upon Reddit SlashDot Ask BlinkBits BlinkList Co.mments Delirious Feed Me Links Google Bookmarks Linkagogo Ma.gnolia MSN Live Netscape Netvouz Newsvine RawSugar Rojo Smarking Socializer Sphinn Spurl Squidoo Tailrank Technorati Yahoo My Web
Post Reply 


Possibly Related Threads...
Thread: Author Replies: Views: Last Post
  Body odor attractiveness as a cue of impending ovulation in women jvkohl 0 349 11-26-2011 9:21 PM
Last Post: jvkohl
  Androstenol – a Steroid Derived Odor Activates the Hypothalamus in Women jvkohl 14 1,173 02-23-2010 10:14 PM
Last Post: jvkohl

Forum Jump:


Login or Register to remove all advertising
True Pheromones
Current time: 05-23-2012, 1:38 PM
Contact Us Home Return to Content Lite (Archive) Mode RSS Syndication Forum Disclaimer